Chained to a wall in an abandoned warehouse, twenty-one year old Lani Jorgenson, the daughter of a minister becomes a vampire. Her creator, Marcus Bronson, lies dead on the floor, his head severed from his body. Lani breaks her bonds and seeks her first victim. With his blood, she gathers the strength she will need to begin her new life. She reads Marcus’s journals and finds out many things, he, once known as Marcellus Bratius, learned in his two thousand years as an immortal.

One hundred and twenty five years later, in 1965, she falls in love with David Forrester. Though she longs for a mate, she cannot bring herself to subject him to a life of vampirism. Lani hypnotizes him to forget her and leaves the area, but David eventually remembers everything and vows to hunt her down and destroy her.

Near the end of the second millennium, Kathleen Hammond, a reporter for the Morning Call, goes to the scene of a death. The stone white corpse of Jason Weber alerts her to the fact that a vampire may really exist. With the help of David and several other believers, they unite to hunt Lani and face her in a final battle of good versus evil.